Cladribine treatment improves cortical network functionality in a mouse model of autoimmune encephalomyelitis.

T cell subsets, NK cells and natural killer T cells (NKT) showed a trend for reduction, although not significant (CD3 + CD4 + T cells: 0.39 ± 0.05 vs. 1.67 ± 0.15 * 10 2 cells/μl; CD3 + CD8 + T cells: 0.16 ± 0.03 vs. 1.03 ± 0.12 * 10 2 cells/μl; NK cells: 0.15 ± 0.03 vs. 1.00 ± 0.25 * 10 2 cells/μl; NKT cells: 0.02 ± 0.01 vs. 0.11 ± 0.03 * 10 2 cells/μl; for all cell subsets p > 0.05).

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The level of significance was labeled according to the p -values: p values > 0.05 were classified as not significant, p < 0.05 (*) as significant, p < 0.01 (**), p < 0.001 (***) and p < 0.0001 (****) as highly significant.

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