Costimulation blockade in combination with IL-2 permits regulatory T cell sparing immunomodulation that inhibits autoimmunity.

Nat Commun · 2022 · PMC9643453 · PMID 36347877

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showed a trendno p-value reported

Mice subsequently treated with Abatacept and IgG-(IL-2) 2 showed a trend towards retention of more functional beta cell mass as judged by glucose tolerance tests (Supplementary Fig. 8 ).

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