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Regulatory variants in a novel distal enhancer regulate the expression of CYP3A4 and CYP3A5.

Clin Transl Sci · 2022 · PMC9652438 · PMID 36045613

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showed a trendno p-value reported
The rs115025140 is unique to the African population and in a clinical cohort of African Americans taking statins for lipid control rs115025140 carriers showed a trend toward reduced statin‐mediated lipid reduction.

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