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CMTM4 is a subunit of the IL-17 receptor and mediates autoimmune pathology.

Nat Immunol · 2022 · PMC9663306 · PMID 36271145

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Cmtm4 −/− mice had a slightly milder EAE progression, based on the combined severity score, compared to Cmtm4 +/+ littermates, albeit the difference did not reach statistical significance (Extended Data Fig. 8f ).

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