Neurons and glial cells acquire a senescent signature after repeated mild traumatic brain injury in a sex-dependent manner.

Front Neurosci · 2022 · PMC9669743 · PMID 36408415

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closest p · 2.0× alpha

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boldest claim

The sentences

nearing significancep < 0.1so close (0.05 < p ≤ 0.1)

A small effect of sex was seen nearing significance ( p < 0.1, three-way ANOVA) resulting in a significant interaction between injury, sex, and training day ( p = 0.05, three-way ANOVA) reflecting baseline differences between male and female sham mice in which female sham mice are performing worse than their male counterparts.

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did not reach statistical significanceno p-value reported

Positive staining for Iba-1 in the same brain regions was increased in injured mice compared to shams ( Figures 1E,F ), although this did not reach statistical significance in the cortical region ( Figure 1G ).

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