Targeted proteomics identifies circulating biomarkers associated with active COVID-19 and post-COVID-19.

Front Immunol · 2022 · PMC9670186 · PMID 36405747

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highly significantno p-value reported

Highly significant proteins in this group are related to the proteolytic balance in the extracellular matrix (ECM) (MMP7 and MMP1) and TNFα signaling pathways (TNFα, TWEAK).

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nominally significantno p-value reported

Proteins were considered replicated when the corresponding gene was nominally significant and directionally concordant with the proteome. 2.6 Predictive modelling Two separate linear regression models were used to predict (i) COVID-19 disease severity and (ii) the time after SARS-CoV-2 infection.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.