RNA biomarkers for alcohol use disorder.

Front Mol Neurosci · 2022 · PMC9673015 · PMID 36407766

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highly significantno p-value reported

Blood expression levels of two genes ( ERCC1 and MCM5 ) showed a highly significant correlation with AUD-induced decreases in the volume of the left parietal supramarginal gyrus and various neuropsychological measures.

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nominally significantno p-value reported

Three of these were identified as either genome-wide or nominally significant by GWAS and were affected by ethanol with a direction opposite those for AUD versus controls: MREG (melanoregulin), CASZ1 (castor zinc finger 1), and ST3GAL1 (ST3 beta-galactoside alpha-2,3-sialyltransferase 1).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.