Barely Significant
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Spatiotemporal dynamics of Plasmodium falciparum histidine-rich protein 2 and 3 deletions in Peru.

Sci Rep · 2022 · PMC9674673 · PMID 36400806

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a clear trendno p-value reported
However, there is a clear trend of increasing prevalence of dual pfhrp2/3 -deleted parasites with time in the study area.

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an increasing trendno p-value reported
In conclusion, we confirmed that there was an increasing trend of dual pfhrp2/3- deleted parasites from 2011 until 2018 in Iquitos that is associated with the spread of a new parasite line (H8) that has replaced previously circulating lineages in Peru.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.