Cabozantinib sensitizes microsatellite stable colorectal cancer to immune checkpoint blockade by immune modulation in human immune system mouse models.

Front Oncol · 2022 · PMC9676436 · PMID 36419897

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Further, we also found that higher PD-L1 expression, which we observed in the combination treated tumors, showed a trend for higher expression among responding combination-treated tumors but was only significantly increased in responding tumors for Ca single treatment.

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