Co-display of diverse spike proteins on nanoparticles broadens sarbecovirus neutralizing antibody responses.

iScience · 2022 · PMC9678814 · PMID 36439375

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did not reach statistical significanceno p-value reported

SARS-CoV-2 S-NPs induced approximately 3-fold higher neutralization titers against SARS-CoV-2 (median ID 50 of 16,792) compared with the other immunogens in mice at week 6, although the difference did not reach statistical significance.

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