Barely Significant
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Performance of polygenic risk scores for cancer prediction in a racially diverse academic biobank.

Genet Med · 2022 · PMC9680700 · PMID 34906489

Europe PMCDOI
1
hedged sentence
0.0600
closest p · 1.2× alpha
0.0600
boldest claim

The sentences

approaching significanceP = .06so close (0.05 < p ≤ 0.1)
Among the cancers with >100 cases of African genetic ancestry, the PRS for thyroid (OR = 1.21, 95% CI = 1.01-1.47, P = .04), colon (OR = 1.29, 95% CI = 1.08-1.53, P = .005), and prostate (OR = 1.40, 95% CI = 1.24-1.58, P = 3.3 × 10 −8 ) were significantly associated with their respective cancer phenotypes ( Figure 1 , Supplemental Table 5 ), and the PRS for breast cancer was approaching significance (OR = 1.12, 95% CI = 0.99-1.26, P = .06).

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