Granzyme B in circulating CD8+ T cells as a biomarker of immunotherapy effectiveness and disability in neuromyelitis optica spectrum disorders.

Front Immunol · 2022 · PMC9682179 · PMID 36439094

Europe PMC DOI

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closest p · 1.1× alpha

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boldest claim

The sentences

did not reach statistical significanceP=0.055so close (0.05 < p ≤ 0.1)

As results, we found a significant association between proportions of GzmB+CD8+ T cells and EDSS scores mainly in the poor-response group (r=0.682, P=0.013), and the same trend was observed in untreated patients, although the difference did not reach statistical significance (r=0.600, P=0.055) ( Figure 3D ).

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