Hydroxychloroquine reduces soluble Flt-1 secretion from human cytotrophoblast, but does not mitigate markers of endothelial dysfunction in vitro.

A trend towards decreased sFlt-1 concentrations was observed in conditioned media from treated explant tissue, however, this did not reach statistical significance ( Fig 1D ).

also in 111,027 other papers

In contrast, addition of hydroxychloroquine (1–20μM) led to a decreasing trend in VCAM expression ( Fig 4E ), compared to vehicle control treated cells.

also in 47,180 other papers