Transcriptome-wide association study and eQTL colocalization identify potentially causal genes responsible for human bone mineral density GWAS associations.

Elife · 2022 · PMC9683789 · PMID 36416764

Europe PMC DOI

hedged sentence

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closest p · 1.0× alpha

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boldest claim

The sentences

nominally significantp ≤ 0.05actually significant

Of the 512, 142 (27.7%) had been tested by the IMPC and 64 (12.5% of the 512 prioritized genes, 45% of the 142 IMPC-tested genes) had a nominally significant (p ≤ 0.05) alteration of whole-body BMD in knockout/knockdown mice, compared to controls.

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