Results showed a trend in the direction of fewer participants being readmitted to hospital in the dose maintenance group in comparison with the dose reduction group, but the 95% confidence interval (CI) did not exclude the possibility of no difference (risk ratio (RR) 1.53, 95% CI 0.84 to 2.81, 9 RCTs, n = 1433 (8 studies and n = 1413 with estimable effect sizes), I 2 = 59% (moderate heterogeneity), very low certainty evidence) ( Analysis 1.1 ).
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Antipsychotic dose reduction compared to dose continuation for people with schizophrenia.
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