Baseline mitochondrial DNA copy number and heart failure incidence and its role in overall and heart failure mortality in middle-aged women.

Front Cardiovasc Med · 2022 · PMC9685522 · PMID 36440036

Europe PMC DOI

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0.1400

closest p · 2.8× alpha

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The sentences

did not reach statistical significancep -value = 0.14not close (p > 0.1)

The mediation analysis showed that although mtDNA-CN affects the risk of MI (OR = 1.48) and MI via a risk of future HF (OR = 8.0), the indirect effect of MI on the association between mtDNA-CN and HF was small and did not reach statistical significance (OR = 1.06; p -value = 0.14) ( Supplementary Table 1 and Figure 3 ).

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