Individualization of Mycophenolic Acid Therapy through Pharmacogenetic, Pharmacokinetic and Pharmacodynamic Testing.

Biomedicines · 2022 · PMC9687418 · PMID 36359401

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highly significantno p-value reported

Predose IMPDH Enzyme Activity in PBMCs and Graft Rejection In the pharmacodynamic analysis, there was a highly significant association between the predose IMPDH enzyme activity in PBMCs and kidney graft rejection ( Table 2 ).

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a clear trendno p-value reported

The results indicated a clear trend showing the association of the rs11706052 SNP status with kidney graft rejection risk, but the sample size in the overall analysis was too small to show statistical significance. 3.3.

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