Maternal Calorie Restriction Induces a Transcriptional Cytoprotective Response in Embryonic Liver Partially Dependent on Nrf2.

Indeed, Chac1 and Ddit3 showed a robust induction (approximately seven-fold and three-fold respectively) ( Figure 2 E,F) in livers of embryos with calorie restriction while Atf4 showed a trend for increase ( Figure 2 D). 3.2.

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