Right Ventricle Remodelling in Left-Sided Heart Failure in Rats: The Role of Calcium Signalling.

The SR Ca 2+ in RV cardiomyocytes was unchanged, but there was a clear trend towards its increase ( p = 0.08) in post-MI animals compared to sham-operated ones ( Figure 3 E).

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SERCA2a activity in the RV cardiomyocytes, in contrast to the LV cardiomyocytes, was preserved and even showed an increasing trend ( Figure 3 F), while the activity of both membrane transporters, NCX1 and PMCA, was significantly reduced ( Figure 3 G and H, respectively).

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