Macrophage-Targeted Sodium Chlorite (NP001) Slows Progression of Amyotrophic Lateral Sclerosis (ALS) through Regulation of Microbial Translocation.

Biomedicines · 2022 · PMC9687998 · PMID 36428474

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highly significantno p-value reported

Note the highly significant difference between the >1.13 CRP NP001 vs. placebo patients as compared to no observable difference in patients with CRP < 1.13 mg/L.

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showed a trendno p-value reported

The results suggested that participants with a higher level of baseline plasma CRP showed a trend towards a slowing ALSFRS-R loss over the six-month trial in patients receiving 2 mg/kg NP001 as compared to placebo.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.