Sarcopenia as a Prognostic Marker in Elderly Head and Neck Squamous Cell Carcinoma Patients Undergoing (Chemo-)Radiation.

Patients treated with primary (chemo)radiation showed a trend towards reduced skeletal muscle mass as compared to those treated postoperatively with 60.1% vs. 46.4% of sarcopenic patients for L3MA ( p = 0.032) and 55.7% vs. 43.3% for L3MI ( p = 0.059) ( Table 1 ).

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The first meta-analysis covering approximately one thousand patients showed a highly significant association of pre- and post-therapeutic sarcopenia with reduced overall survival in 7 studies with median patient ages of 57–66 years.

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