moderately significantp -value = 9.12893 × 10 −05
Pathways Analysis Gene ontology and pathway enrichment of the top 50 genes revealed that the migraine subjects are moderately significant for the organic hydroxy compound catabolic process (GO:1901616; p -value = 9.12893 × 10 −05 ; adjusted p -value = 0.026108731) and quinone metabolic process (GO:1901661; p -value = 0.000272123; adjusted p -value = 0.038913602) ( Table 5 ; Supplementary Table S2 ).