Barely Significant
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Exploring the Association of HLA Genetic Risk Burden on Thalamic and Hippocampal Atrophy in Multiple Sclerosis Patients.

Genes (Basel) · 2022 · PMC9690825 · PMID 36421810

Europe PMCDOI
1
hedged sentence
0.0470
closest p · 0.9× alpha
0.0470
boldest claim

The sentences

nominally significantp = 0.047actually significant
In the evaluation of the cumulative influence of the 29 HLA loci on atrophy metrics, adjusted models revealed a marginal correlation between higher HLAGB and decreased volume of hippocampus (β = −0.142, p = 0.063) and a nominally significant association with lower thalamic volume (β = −0.299, p = 0.047), although not upon multiple testing correction.

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