A Novel Ketone-Supplemented Diet Improves Recognition Memory and Hippocampal Mitochondrial Efficiency in Healthy Adult Mice.

Metabolites · 2022 · PMC9693360 · PMID 36355101

Europe PMC DOI

hedged sentences

0.0530

closest p · 1.1× alpha

0.1200

boldest claim

The sentences

a strong trend toward significancep = 0.053so close (0.05 < p ≤ 0.1)

A strong trend toward significance was observed with the addition of glutamate and malate (O GM , p = 0.053), which support complex I-mediated respiration associated with the proton leak.

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a trend toward significancep = 0.12not close (p > 0.1)

However, the discrimination index, a measure of the mouse’s ability to discriminate the novel from familiar object, indicated a trend toward significance ( Figure 2 B; p = 0.12).

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