Multivariable regression identified age as the most influential variable, showing a strong trend toward significance ( p = 0.051), while PLR was not an independent predictor ( p = 0.197).
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However, when entering the perioperative low cardiac output, a well-recognized predictor of hospital death, and AST in a multivariable analysis, both variables maintained a strong trend toward significance in predicting early mortality ( p = 0.052, OR [95% CIs] = 1.04 [1–1.08] for AST; and p = 0.048, OR [95% CIs] = 6.9 [1.06–45.0] for low cardiac output).
This was significantly higher than the observation group (19.2%, p = 0.009, z-test) and showed a strong trend toward significance compared to the adjuvant group (32.1%, p=0.053, z-test).
Biological Pathway Insights Two pathways were notably altered: alanine, aspartate and glutamate metabolism was the most significantly disturbed pathway in both enrichment and topology analyses ( p < 0.05 for both), and tryptophan metabolism was significantly altered in the enrichment analysis while showing a strong trend toward significance ( p = 0.058) in the topology analysis.
The mean CLH2 expression differed significantly, and 45M1 had a strong trend toward significance ( p = 0.06) among the three groups ( Figure 1 B).
Lower NIHSS scores at admission showed a strong trend toward significance (OR: 0.716, 95% CI: 0.505–1.015, P=0.061).
The Charleson Comorbidity Index (CCI) showed a strong trend toward significance ( p = 0.065), while age lost statistical significance after adjusting for comorbidities.
Similary, a strong trend toward significance was observerd for OS (18.04 vs 12.09 mo; HR: 0.53 [0.25–1.29] p = 0.07) (Fig. 4 ).
Consistent with these findings, biochemical assessment of complex-V (ATP synthase) activity revealed that LPS exposure reduced enzymatic activity relative to sham controls, with a strong trend toward significance ( p = 0.08; Fig.
The improvement over the 3DT1W MRI model showed a strong trend toward significance ( z = −1.735, p = 0.083).
The univariate analysis included all the factors exhibiting significance in the association between post-CRT RIT rates and the baseline or treatment-related characteristics, while the multivariate logistic regression analysis included only the factors exhibiting significance or a strong trend toward significance ( P < 0.10) in the univariate analysis.
They found no changes in aerobic capacity indicators (but a strong trend toward significance for KF DP ), while they did find a significant increase in KF MAX and K TOTAL , indicating an improvement in aerobic power.
Stent thrombosis was also significantly reduced with the use of IVUS in 4 meta-analyses, with the meta-analysis by Saleem et al 65 showing a strong trend toward significance.
Regarding in-hospital mortality, dementia emerged as a significant independent risk factor, while chronic liver disease showed a strong trend toward significance.
Although animals receiving either ISP or PNNi alone did not show a similar effect of meaningful forelimb functional recovery as we showed in the FLS assessment, these animals did show a strong trend toward significance by the end of the study compared with the control group ( Figs. 4 and 5 ).
We found that the μKO mice had enhanced capability to travel further distances in the open field test compared to the WT at 24 h and showed a strong trend toward significance at 48 h after injury (Fig. 9 A–D).
The variation in the glycemia delta (post minus pre-breakfast) on the seventh day of the study showed a p -value of 0.051, indicating a strong trend toward significance.
Asthma remained significant in patients with clinical allergy, and clinical allergy showed a strong trend toward significance in patients with asthma.
There were no significant differences in leptin levels either before or after puberty between ASD+/Ob+ and ASD−/Ob+ or between ASD+/Ob− and ASD−/Ob−, although there was a strong trend toward significance for higher pre-pubertal leptin levels in ASD+/Ob− than in ASD−/Ob−.