MLN4924 Treatment Diminishes Excessive Lipid Storage in High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease (NAFLD) by Stimulating Hepatic Mitochondrial Fatty Acid Oxidation and Lipid Metabolites.

The nocturnal O 2 consumption, CO 2 production and heat of mice from the HFD-MLN4924 group showed a trend of increase compared with those from the HFD-Control group, although there were no statistical differences ( Figure 5 a–d).

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