Combined Neuro-Humoral Modulation and Outcomes in Patients with Chronic Heart Failure and Mildly Reduced or Preserved Ejection Fraction.

J Clin Med · 2022 · PMC9697286 · PMID 36431103

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a clear trendno p-value reported

Importantly, even if double NHM therapy was not as effective as triple NHM in improving patient outcomes, a clear trend of a possible beneficial effect was present even with double treatment at least in HFmrEF (HR 0.889, 95% CI 0.683–1.156).

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