Importantly, the addition of TAC did not appear to adversely impact the efficacy of NM; in fact there was an improvement noted in the combination treatment group, though this did not reach statistical significance. 16 The product insert for NM gel 17 recommends daily application to affected areas of skin in accordance with the frequency used in the registration trial. 9 In the 2-year observational PROVe study, patterns of use and response of NM gel in a real-world cohort of patients with MF was described.
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Mechlorethamine Hydrochloride Gel in the Treatment of Mycosis Fungoides-Type Cutaneous T-Cell Lymphoma (MF-CTCL): A Focus on Patient Selection and Special Considerations.
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