Research on skeletal muscle impact injury using a new rat model from a bioimpact machine.

Meanwhile, the gastrocnemius showed a trend of “edema-mitochondrial vacuolation-inflammatory cell aggregation” after impact injury.

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Our experiments showed that the edema of lower limbs was serious on the first day after the injury, the vacuolation of mitochondria reached its peak on the second day, and the inflammatory cell infiltration was the most on the third day, showing an overall trend of “edema-mitochondrial vacuolation-inflammatory cell aggregation.” In terms of causing gait changes, dysregulation of Ca 2+ metabolism may be another important factor besides pain.

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