Using genetic instruments to estimate the causal effect of hormonal reproductive factors on osteoarthritis.

However, as shown in Table 1 and Figure 1 , some nominally significant positive causality correlations with OA did not pass multiple-testing correction for the Bonferroni method (hip OA: OR = 0.76, 95% CI: 0.51–1.00, P = 2.65 × 10 −2 ; knee OA: OR = 0.81, 95% CI: 0.63–0.98, P = 1.57 × 10 −2 ).

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