Impact of cardiac resynchronization therapy optimization inside a heart failure programme: a real-world experience.

In the VVd optimization group, more patients became responders at 9 months, but this difference did not reach statistical significance and results were only published in abstract form. 18 Among initial non‐responders from our real‐life study, the rate of CCS improvement at 6 months from optimization as well as the rate of major HF events were not statistically different between VVd modified patients and those with already optimal VVd.

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