A systematic review and meta-analysis of interventional studies of bisphosphonates and denosumab in multiple myeloma and future perspectives.

J Musculoskelet Neuronal Interact · 2022 · PMC9716295 · PMID 36458395

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did not reach statistical significanceno p-value reported

ZOL was superior to CLOD in increasing overall PFS by 2 months, (HR 0.88;95% CI,0.80–0.98), but when the same outcome was assessed separate for the intensive and non-intensive pathway, it did not reach statistical significance (HR 0.90;95% CI, 0.78–1.05 and HR 0.87;95% CI, 0.74–1.01 respectively).

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