The Developmental Progression of Eight Opsin Spectral Signals Recorded from the Zebrafish Retinal Cone Layer Is Altered by the Timing and Cell Type Expression of Thyroxin Receptor β2 (trβ2) Gain-Of-Function Transgenes.

In the best-fitting model for gnat2:mYFP-2A-trβ2;mpv17 −/− adults, the long-wavelength R1 cone (Vr575) contributes the largest amplitude signal with the R2 amplitude (Vr556) being only 22% as large, significantly less than R1 ( t (2748) = 5.23, p = 2.6 × 10 −17 ), and the gnat2:trβ2 R1 amplitudes are only marginally significant ( t (1375) = 2.02, p = 0.044; Fig. 10 C ).

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