Long-term, NTD responders showed a trend toward decreasing EPO levels [ Figure 2(a) ].
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Long-term safety and erythroid response with luspatercept treatment in patients with β-thalassemia.
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Reticulocyte levels in NTD erythroid responders, after an initial rise from baseline, showed a decreasing trend, whereas in nonresponders, the rising trend lasted throughout the base study and extension phase [ Figure 2(c) ].