Precursor-Directed Synthesis of Apoptosis-Initiating N-Hydroxyalkyl Phenylbenzoisoquinolindione Alkaloids.

ChemistryOpen · 2022 · PMC9728486 · PMID 36478420

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showed a trendno p-value reported

Compounds 30 , 32 , 34 , 36 , 38 , and 40 , all of which had a 5‐OH group, showed a trend towards increasing activity with increasing N ‐hydroxyalkyl chain lengths (Table 2 ).

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