Although the association between AA race and ICI%≥5 after adjusting for age, diabetes duration, sex, BMI and TCF7L2 variant did not reach statistical significance ( p =0.053), the association between TCF7L2 variants and higher ICI% was significantly stronger in AA donors than in other races ( p= 0.0167).
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Milder loss of insulin-containing islets in individuals with type 1 diabetes and type 2 diabetes-associated TCF7L2 genetic variants.
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0.0530
0.0530