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Short-term dynamics of circulating tumor DNA predicting efficacy of sintilimab plus docetaxel in second-line treatment of advanced NSCLC: biomarker analysis from a single-arm, phase 2 trial.

J Immunother Cancer · 2022 · PMC9730395 · PMID 36600554

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However, the difference did not reach statistical significance, and whether mutant PIK3CG or GRIN2A was a protective factor needs to be illustrated in the future.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.