The analysis showed a trend towards a decrease in IL-6 levels following the exercise intervention, but there was no statistically significant difference in IL-6 levels between the exercise group and the control group (WMD, -0.479 pg/ml; 95% CI, -1.107 to 0.149, p = 0.195).
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Effects of exercise on inflammatory factors and IGF system in breast cancer survivors: a meta-analysis.
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There was an increasing trend in IGFBP-3 levels after the exercise intervention, but the effect of exercise on IGFBP-3 levels was not significant (WMD, 4.501 ng/ml; 95% CI, -1.099 to 10.101; P = 0.115).
This is similar to the findings of our study, which found a nonsignificant trend of improved IGFBP-3 levels after exercise.