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Increased tumor glycolysis is associated with decreased immune infiltration across human solid tumors.

Front Immunol · 2022 · PMC9731115 · PMID 36505421

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Notably, we found that increased expression of glycolytic markers was associated with poor prognosis (HR 3.44, p = 0.0529), whereas a numerical association between stromal immune infiltration and longer RFS (HR = 1.2e -8 , p = 0.99) was observed, although this analysis did not reach statistical significance, likely due to the small sample size and number of events ( Supp Figure S13C ).

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