White matter abnormalities in the <i>Hdc</i> knockout mouse, a model of tic and OCD pathophysiology.

No significant differences were found between Hdc -KO mice and WT controls in overall dorsal striatum or in anterior or posterior subregions; if anything, the trend was toward reduced oligodendrocyte density in KO mice, though this did not reach statistical significance ( Figures 3A,B ).

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