As shown in Figure 5 A, lung tissues from mouse HPH showed a trend in increased YAP1 expression; however, rat MCT and rat Sugen + hypoxia showed significantly higher levels of YAP1 expression compared with control lungs ( Figure 5 B,C).
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Sphingosine Kinase 1 Deficiency in Smooth Muscle Cells Protects against Hypoxia-Mediated Pulmonary Hypertension via YAP1 Signaling.
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