Next, chromosome enumeration in 1CT cells revealed 2.9–4.0-fold increases in the frequency of aberrant chromosome spreads that were determined to be significant ( Figure 5 D,E, Table S8 ) within the siSKP2-4 condition, with the siSKP2-3 and siSKP2-Pool conditions trending towards significance ( p -values = ~0.10).
← all excerpts
Reduced <i>SKP2</i> Expression Adversely Impacts Genome Stability and Promotes Cellular Transformation in Colonic Epithelial Cells.
1
—
—