Heavy silicone oil tamponade: a multicentre experience.

BMJ Open Ophthalmol · 2022 · PMC9743375 · PMID 36710637

Europe PMC DOI

hedged sentences

0.0590

closest p · 1.2× alpha

0.0670

boldest claim

The sentences

failed to reach statistical significancep=0.059so close (0.05 < p ≤ 0.1)

While it failed to reach statistical significance (p=0.059), this difference may suggest greater efficacy of Densiron 68 in such cases. 18 In contrast the HSO study, a multicentre randomised masked controlled trial by Joussen et al, suggested lower reattachment rates with HSO (28.3%) compared with standard silicone oil (1000 or 5000 centistokes; 40.4%) in the treatment of complicated inferior RRD. 15 This trial also failed to show statistical difference between the two different oil tamponades in terms of reattachment rates or VA at 12 months follow-up.

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did not quite reach statistical significancep=0.067so close (0.05 < p ≤ 0.1)

Eleven patients (8.2%) had long-term Densiron 68 retention, while failure was seen in 24 patients (17.9%) There was a trend for higher final reattachment rate after Densiron 68 removal for recurrent RRD (68 eyes (79.1%)) compared with those who had primary RRD (31 eyes (64.6%)) although this did not quite reach statistical significance ( table 3 ; p=0.067).

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