An observational study of the factors associated with frequency of outpatient benzodiazepine prescribing to patients receiving chronic opioid analgesic therapy in primary care at a major academic center.

BMC Prim Care · 2022 · PMC9749278 · PMID 36513985

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showed a trendno p-value reported

In another study, patients with chronic pain who were diagnosed with alcohol use disorder showed a trend toward longer opioid use [ 19 ].

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