observed between LABA/LAMA and placebo in a single study (n = 125) did not reach statistical significance (Table 2 ); however, the meta-analysis of results of the 4 studies comparing LAMA/LABA with monotherapies (n = 634) showed significant differences in 6MWT in favour of LAMA/LABA combination (Table 2 ; Fig. 2 c).
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Exercise capacity and physical activity in COPD patients treated with a LAMA/LABA combination: a systematic review and meta-analysis.
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