An amino-terminal fragment of apolipoprotein E4 leads to behavioral deficits, increased PHF-1 immunoreactivity, and mortality in zebrafish.

PLoS One · 2022 · PMC9754248 · PMID 36520946

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did not reach statistical significanceno p-value reported

Behaviorally, touch-evoked responses to stimulus were negatively impacted by treatment with nApoE4 1-151 but did not reach statistical significance.

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just missed significanceno p-value reported

Interesting, results for these new data, total swimming distance (p=.08) and swimming time (p=.06) just missed significance as compared to untreated controls.

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