cDC1-derived IL-27 regulates small intestinal CD4+ T cell homeostasis in mice.

J Exp Med · 2023 · PMC9754766 · PMID 36515659

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1 A ), 36-d-old Xcr1-cre .DTA mice had a reduced total number of SI-LP CD4 + T cells and a marked reduction in SI-LP Th1 cells compared with Cre − controls, and while Th17 numbers showed a trend toward higher numbers, this was not significant ( Fig. 4 A ).

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