Hepatic neddylation deficiency triggers fatal liver injury via inducing NF-κB-inducing kinase in mice.

S8i ), B022 significantly attenuated the expression of inflammatory genes (e.g., Lgals3 , but not Ccl2 ) and showed a trend, though not statistically significant, toward suppressing the activation of progenitor genes ( Krt19 , Pkm ) in AAV-Cre livers (Fig. 6i ).

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