Rosiglitazone Reverses Inflammation in Epididymal White Adipose Tissue in Hormone-Sensitive Lipase-Knockout Mice.

Cer 42:2 (d18:1/24:1) levels were increased in untreated Hsl knockout mice and only showed a slight trend of higher levels after rosiglitazone treatment ( Fig. 8 D).

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Gene expression of the ER stress markers, Erdj4 , Bip/Grp78 , and Chop , was also significantly increased in iWAT, whereas Edem expression only showed a trend toward increased expression ( Fig. 1 D).

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