Spatiotemporal evolution of the clear cell renal cell carcinoma microenvironment links intra-tumoral heterogeneity to immune escape.

Genome Med · 2022 · PMC9762114 · PMID 36536472

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did not reach statistical significanceno p-value reported

However, the association between genomic ITH and myeloid infiltration did not reach statistical significance in TCGA KIRC cohort suggesting the association between myeloid infiltration and ITH is likely indirect through certain genomic events such as CDKN2A/B loss.

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